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>   home   >   Products   >   Primary Antibodies   >   Anti Rat CD86 Antibody, clone 24F    

Anti Rat CD86 Antibody, clone 24F

Mouse Anti-Rat Monoclonal Antibody

  • IHC - Anti Rat CD86 Antibody, clone 24F  ABD12483
    Immunoperoxidase staining of rat lymph node cryosection with Mouse anti Rat CD86 antibody, clone 42F followed by horseradish peroxidase conjugated Goat anti Mouse IgG . High power
  • FC - Anti Rat CD86 Antibody, clone 24F  ABD12483
    Staining of rat splenocytes with Mouse anti Rat CD86:FITC
  • FC - Anti Rat CD86 Antibody, clone 24F  ABD12483
    Staining of rat splenocytes with Mouse anti Rat CD86:Low Endotoxin
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Rat
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 24F
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen HTLV-1 transformed Lewis-S1 cells.
Shelf Life 18 months from the date of despatch
Target/Specificity Mouse anti Rat CD86 antibody, clone 24F recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Mouse anti Rat CD86 antibody, clone 24F has been shown to block the co-stimulatory activity of rat CD86 (Maedaet al.1997).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Rat CD86 Antibody, clone 24F is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD12483
(40 western blots)
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