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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti Mouse CD178 Antibody, clone MFL4    

Anti Mouse CD178 Antibody, clone MFL4

Hamster Anti-Mouse Monoclonal Antibody

  • FC - Anti Mouse CD178 Antibody, clone MFL4  ABD12502
    Staining of mouse CD178 transfected cells with Hamster anti Mouse CD178:FITC
  • FC - Anti Mouse CD178 Antibody, clone MFL4  ABD12502
    Staining of mouse CD178 transfected cells with Hamster anti Mouse CD178:RPE
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P41047
Reactivity Mouse
Host Hamster
Clonality Monoclonal
Isotype IgG
Clone Names MFL4
Calculated MW 31442 Da
Additional Information
Other Species Rat
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen B6 mouse FasL/BHK cells
Shelf Life 18 months from date of despatch.
Gene ID 14103
Other Names Tumor necrosis factor ligand superfamily member 6, CD95 ligand, CD95-L, Fas antigen ligand, Fas ligand, FasL, CD178, Tumor necrosis factor ligand superfamily member 6, membrane form, Tumor necrosis factor ligand superfamily member 6, soluble form, Receptor-binding FasL ectodomain, Soluble Fas ligand, sFasL, ADAM10-processed FasL form, APL, FasL intracellular domain, FasL ICD, SPPL2A-processed FasL form, SPA, Faslg, Apt1lg1, Cd95l, Fasl, gld, Tnfsf6
Target/Specificity Hamster anti Mouse CD178 antibody, clone MFL4 recognizes both mouse and rat CD178, otherwise known as Fas Ligand/ CD95L, a 40 kDa type II transmembrane glycoprotein and member of the TNF/NGF superfamily, expressed by activated T cells and NK cells, which can be induced on a variety of cells by radiation, heat shock, chemotherapeutic agents and viral infection.CD178 acts as a key effector of cytotoxicity and in the regulation of immune responses. The binding of CD178 to its receptor CD95 (Fas), induces Fas-mediated apoptosis of target cells, and may be involved in the induction of peripheral tolerance and neutrophil chemotaxis. The binding of decoy receptor 3 (DcR3) to CD178 has been shown to inhibit CD178-mediated apoptosis.Hamster anti Mouse CD178 antibody, clone MFL4 is reported to block CD178/CD95 induced apoptosis.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Mouse CD178 Antibody, clone MFL4 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12502
(40 western blots)
Availability: Inquire
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