|Application ||WB, E|
|Calculated MW||23954 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Recombinant human AID (amino acids 1-54) purified from E. coli.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Single-stranded DNA cytosine deaminase, 188.8.131.52, Activation-induced cytidine deaminase, Cytidine aminohydrolase, AICDA, AID|
|Target/Specificity||Mouse anti Human AID, clone 2D3 recognizes human AID (activation-induced cytidine deaminase), a 24kDa RNA-editing enzyme essential for the initiation of immunoglobulin class switch recombination (CSR). somatic hypermutation (SHM) and gene conversion (Honjoet al.2002).AID is selectively expressed by germinal centre B cells and B cell-derived lymphomas, and that a deficiency in AID is responsible for the autosomal recessive form of the immunodeficient condition Hyper-IgM syndrome (Revyet al.2000).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human AID Antibody, clone 2D3 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.