|Application ||WB, E|
|Calculated MW||23954 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Recombinant human AID (amino acids 1-54) purified from E. coli.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Single-stranded DNA cytosine deaminase, 188.8.131.52, Activation-induced cytidine deaminase, Cytidine aminohydrolase, AICDA, AID|
|Target/Specificity||Mouse anti Human AID, clone 2D3 recognizes human AID (activation-induced cytidine deaminase), a 24kDa RNA-editing enzyme essential for the initiation of immunoglobulin class switch recombination (CSR). somatic hypermutation (SHM) and gene conversion (Honjoet al.2002).AID is selectively expressed by germinal centre B cells and B cell-derived lymphomas, and that a deficiency in AID is responsible for the autosomal recessive form of the immunodeficient condition Hyper-IgM syndrome (Revyet al.2000).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human AID Antibody, clone 2D3 is for research use only and not for use in diagnostic or therapeutic procedures.|
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