|Application ||WB, E|
|Calculated MW||147254 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Recombinant human CD45 (amino acids 1029-1249) purified from E. coli.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Receptor-type tyrosine-protein phosphatase C, 188.8.131.52, Leukocyte common antigen, L-CA, T200, CD45, PTPRC, CD45|
|Target/Specificity||Mouse anti Human CD45, clone 3G4 specifically recognises human CD45, otherwise known as LCA (leucocyte common antigen), a type I transmembrane glycoprotein and member of the protein-tyrosine phosphatase (PTP) family, expressed at high levels on all nucleated cells of haematopoietic origin, and which exists in several isoforms generated by the alternative splicing.CD45 is a signal transduction protein vital for T and B cell antigen receptor-mediated activation, and is involved in many aspects of cellular processes, including growth, differentiation and oncogenic transformation. Studies have reported associations between CD45 and many cell surface antigens, including CD2, CD3, CD4, CD26 and CD90, and CD45 is used as a diagnostic histological antibody to distinguish between lymphoma and carcinoma sections.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human CD45 Antibody, clone 3G4 is for research use only and not for use in diagnostic or therapeutic procedures.|
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