|Application ||WB, E|
|Calculated MW||63368 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Recombinant human CD73 (amino acids 27-252) purified from E. coli.|
|Shelf Life||18 months from date of despatch.|
|Other Names||5'-nucleotidase, 5'-NT, 220.127.116.11, Ecto-5'-nucleotidase, CD73, NT5E, NT5, NTE|
|Target/Specificity||Mouse anti Human CD73, clone 2B6 recognises human CD73, otherwise known as ecto-5'-nucleotidase, a GPI-anchored enzyme and member of the 5'-nucleotidase family, which catalyzes the dephosphorylation of 5'-mononucleotides into their corresponding nucleosides, and can also mediate co-stimulatory signals in T cell activation (Dianzaniet al.1993).CD73 is expressed by subpopulations of T and B lymphocytes, and increases during lymphocyte development, acting as a lymphocyte maturation marker. A decrease in CD73 activity has been associated with several immunodeficiency disorders including AIDS and Wiskott-Aldrich syndrome, and CD73 is expressed on a variety of lymphomas and leukaemias, including CLL and ALL (Zhaoet al.2011)|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human CD73 Antibody, clone 2B6 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.