|Calculated MW||26414 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Recombinant human adiponectin purified from E.coli.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Adiponectin, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, apM-1, Gelatin-binding protein, ADIPOQ, ACDC, ACRP30, APM1, GBP28|
|Target/Specificity||Mouse anti Human Adiponectin antibody, clone Adn36 recognizes human adiponectin, also known as Acrp30, 30 kDa adipocyte complement-related protein, Adipocyte, C1q and collagen domain-containing protein or Gelatin-binding protein. Adiponectin is a 244 amino acid major adipokine secreted into the bloodstream from adipose tissue to modulate metabolism, including glucose regulation and fatty acid catabolism (UniProt: Q15848). Adiponectin circulates as three distinct oligomeric forms, trimers (LMW), hexamers (MMW) and dodecamers-octodecamers (HMW) with distinct functions in various target tissues (Wanget al.2008).Adiponectin is involved in regulation of circulating glucose levels and in regulation of insulin sensitivity. Concentrations of adiponectin are reduced in obesity associated metabolic and vascular disorders (Fasshaueret al.2004) in particular lower circulating levels of HMW adiponectin correleates with the appearance of type II diabetes and acts as a predictor for this condition (Zhuet al.2010).Mouse anti human adiponectin antibody, clone Adn36 has been used successfully in the development of a sensitive sandwich ELISA in conjunction with mouse anti human adiponectin antibody, clone 5H7 as a detection reagent for the measurement of circulating levels of adiponectin in human serum.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human Adiponectin Antibody, clone Adn36 is for research use only and not for use in diagnostic or therapeutic procedures.|
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