|Application ||WB, E|
|Calculated MW||23010 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Human recombinant Retinol Binding Protein 4|
|Shelf Life||18 months from date of despatch.|
|Other Names||Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176), RBP4|
|Target/Specificity||Mouse anti Human Retinol Binding Protein 4 antibody, clone RB48 recognizes human serum Retinol Binding Protein 4 (RBP4), a single-chain glycoprotein belonging to the lipocalin family, which is responsible for the transport of Retinol (vitamin A1) from the liver to peripheral target tissues. In plasma, the RBP4-retinol complex interacts with transthyretin preventing its loss through filtration through the kidney glomeruli. Defects in RBP4 are a cause of retinol-binding protein deficiency and can cause night vision problems. RBP4 has been described as an adipokine that contributes to insulin resistance in mice. Mouse anti Human Retinol Binding Protein 4 antibody, clone RB48 recognizes free RBP4 and RBP4 in complex with transthyretin. It reacts with apo- as well as holo-RBP4. It recognizes human RBP4 in western blotting under reducing conditions.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human Retinol Binding Protein 4 Antibody, clone RB48 is for research use only and not for use in diagnostic or therapeutic procedures.|
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