|Calculated MW||11981 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Other Names||Insulin, Insulin B chain, Insulin A chain, INS|
|Target/Specificity||Mouse anti Human C-Peptide antibody, clone 5B8 recognizes human C-peptide. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+ -ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Levels of C-peptide can be used to distinguish between type 1 and type 2 diabetes. Patients with type 1 diabetes will usually have decreased levels of C-peptide, while patients with type 2 diabetes will have normal or higher than normal levels.Mouse anti Human C-Peptide antibody, clone 5B8 does not cross-react with human, bovine, porcine, mouse or rat insulin.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human C-Peptide Antibody, clone 5B8 is for research use only and not for use in diagnostic or therapeutic procedures.|
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