|Calculated MW||21396 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Activated NK (A-LAK) cells from B6 (H-2b) mice.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Killer cell lectin-like receptor subfamily G member 1, Mast cell function-associated antigen 2F1, Klrg1, Mafa|
|Target/Specificity||Hamster anti Mouse KLRG1 antibody, clone 2F1 recognizes mouse KLRG1 (killer cell lectin-like receptor G1), the mouse homolog of the rat mast cell function-associated antigen (MAFA). It is expressed by activated CD8 T-cells and by a large proportion of natural killer (NK) cells. It is not found in the spleen, thymus, lymph nodes, testis, brain or kidney and is not expressed on mast cell lines, bone-marrow-derived mast cells or peritoneal mast cells. T-cells expressing KLRG1 have greatly reduced proliferation potential, but are not limited in their capacity to perform immediate effector cell functions, such as the secretion of gamma interferon. KLRG1 plays an inhibitory role on NK cells and T-cells by binding to their ligands.|
|Preservative & Stabilisers||0.09% Sodium Azide, 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse KLRG1 Antibody, clone 2F1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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