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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti Mouse CD137 Antibody, clone 17B5    

Anti Mouse CD137 Antibody, clone 17B5

Hamster Anti-Mouse Monoclonal Antibody

  • FC - Anti Mouse CD137 Antibody, clone 17B5  ABD12571
    ConA activated mouse spleen cells stained with hamster anti mouse CD137:FITC
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P20334
Reactivity Mouse
Host Hamster
Clonality Monoclonal
Isotype IgG
Clone Names 17B5
Calculated MW 27598 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Shelf Life 18 months from date of despatch.
Gene ID 21942
Other Names Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, T-cell antigen 4-1BB, CD137, Tnfrsf9, Cd137, Ila, Ly63
Target/Specificity Hamster anti Mouse CD137 antibody, clone 17B5 recognizes mouse CD137, also known as 4-1BB ligand receptor, a member of the tumour necrosis factor superfamily. CD137 is a potent costimulatory receptor for the growth and functional maturation of activated T-cells in the presence of T-cell receptor signal. It is found on activated T-cells, NK cells, monocytes and dendritic cells. Signalling through CD137 triggers T-cell expansion, cytokine production and prevention of activation-induced death of effector T-cells. CD137-mediated activation is distinct from and independent of CD28. Antibody cross-linking of CD137 on NK cells stimulates the secretion of IFN-gamma, cellular proliferation, CD25 expression and responsiveness to IL-2 and is associated with tumour activity, but not cytotoxicity.Hamster anti Mouse CD137 antibody, clone 17B5 may be used to block CD137-mediated T-cell proliferation.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Mouse CD137 Antibody, clone 17B5 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12571
(40 western blots)
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