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Anti Human Dectin-1 Antibody, clone BD6

Mouse Anti-Human Monoclonal Antibody

     
  • FC - Anti Human Dectin-1 Antibody, clone BD6  ABD12573
    Staining of human peripheral blood granulocytes with Mouse anti Human Dectin-1:RPE
  • FC - Anti Human Dectin-1 Antibody, clone BD6  ABD12573
    Staining of human peripheral blood granulocytes with Mouse anti Human Dectin-1:Alexa Fluor® 488
  • FC - Anti Human Dectin-1 Antibody, clone BD6  ABD12573
    Staining of human peripheral blood monocytes with Mouse anti Human Dectin-1:FITC
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC
Primary Accession Q9BXN2
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names BD6
Calculated MW 27627 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen NIH3T3 cells expressing full length Beta-glucan receptor.
Shelf Life 18 months from the date of despatch
Gene ID 64581
Other Names C-type lectin domain family 7 member A, Beta-glucan receptor, C-type lectin superfamily member 12, Dendritic cell-associated C-type lectin 1, DC-associated C-type lectin 1, Dectin-1, CLEC7A, BGR, CLECSF12, DECTIN1
Target/Specificity Mouse anti Human Dectin-1 antibody, clone BD6 recognizes human Dectin-1, also known as beta-glucan receptor (ßGR), a C-type lectin domain family member. It is a major pathogen pattern-recognition receptor that binds beta-glucans, glucose polymers that form cell-wall components or exopolymers of yeasts, fungi and some bacteria. Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, yeast, viral and protozoan infections, as well as tumor formation. Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response. It is highly expressed on peripheral blood leukocytes and dendritic cells.Human Dectin-1 has two major (ßGR-A and ßGR-B) and several minor isoforms. ßGR-A and ßGR-B differs by the presence and absence, respectively, of a stalk region. Mouse anti Human Dectin-1 antibody, clone BD6 recognizes ßGR-A only.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human Dectin-1 Antibody, clone BD6 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12573
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(40 western blots)
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