|Application ||WB, E|
|Calculated MW||51594 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Purified human factor VII.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Coagulation factor VII, 220.127.116.11, Proconvertin, Serum prothrombin conversion accelerator, SPCA, Eptacog alfa, Factor VII light chain, Factor VII heavy chain, F7|
|Target/Specificity||Mouse anti Human Factor VII antibody, clone RFF-VII/1 recognizes Factor VII, a serine protease found circulating in the blood. It initiates the extrinsic pathway of blood coagulation in conjunction with tissue factor. Tissue factor is found on the outside of blood vessels. When the vessels is damaged, tissue factor is exposed to the blood and circulating Factor VII. Once bound to tissue factor, Factor VII is activated by different proteases and converts Factor IX to IXa. Factor VII deficiency is a rare hereditary haemorrhagic disease. Symptoms range from mild to severe. Clone RFF-VII/1 is a strong inhibitor of Factor VII activity. It may be used to detect Factor VII in immunoassays in combination with clone RFF-VII/2 as a capture reagent.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human Factor VII Antibody, clone RFF-VII/1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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