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Anti Bovine GFAP Antibody, clone 4A11

Mouse Anti-Bovine Monoclonal Antibody

  • WB - Anti Bovine GFAP Antibody, clone 4A11  ABD12592
    Rat cerebrum lysate probed with Mouse anti Bovine GFAP followed by Rabbit F(ab')2 anti mouse IgG:HRP
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P14136
Other Accession P03995, Q28115, P47819
Reactivity Bovine
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names 4A11
Calculated MW 49880 Da
Additional Information
Other Species H,M,Rat,Sh,Dog,Pig,Rb,Gp,C
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Bovine spinal cord homogenate.
Shelf Life 18 months from date of despatch.
Gene ID 2670
Other Names Glial fibrillary acidic protein, GFAP, GFAP
Target/Specificity Mouse anti Bovine GFAP antibody, clone 4A11 recognizes glial fibrillary acidic protein, or GFAP, a class III intermediate filament. During development of the central nervous system, GFAP distinguishes astrocytes from other glial cells. It is involved in various cellular functions, such as cell structure and movement, cell communication and the functioning of the blood-brain barrier. It also plays a role in mitosis by adjusting the filament network present in the cell. Defects in GFAP are a cause of Alexander disease, a rare disorder of the central nervous system affecting mostly males. It is a progressive leukoencephalopathy resulting in mental and physical retardation, dementia, seizures and early death. Mouse anti Bovine GFAP antibody, clone 4A11 may be used in conjunction with clones 1B4and2E1 for increased sensitivity when used in immunohistology.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Bovine GFAP Antibody, clone 4A11 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12592
(40 western blots)
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