|Calculated MW||105975 Da|
|Purification||Purified IgG prepared by affinity chromatography|
|Shelf Life||18 months from date of despatch.|
|Other Names||Probable ATP-dependent RNA helicase DDX58, 126.96.36.199, DEAD box protein 58, RIG-I-like receptor 1, RLR-1, Retinoic acid-inducible gene 1 protein, RIG-1, Retinoic acid-inducible gene I protein, RIG-I, Ddx58|
|Target/Specificity||Rat anti Mouse RIG-I antibody, clone SS1A recognises mouse Probable ATP-dependent RNA helicase DDX58, also known as RIG-1, Retinoic acid-inducible gene 1 protein, DEAD-box protein 58 or RIG-I-like receptor 1. RIG-I is a 926 amino acid ~105 kDa innate immune receptor found in the cytoplasm that recognises viral RNA from replicating viruses in infected cells. Upon activation with intracellular RNA, a cascade is triggered resulting in the activation of NF-kappa-B, and the eventual induction of antiviral cytokines such as IFN-beta and RANTES. RIG-I is essential for the production of interferons in response to RNA viruses and as such play a key role in innate immunity (Katoet al.2005).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse RIG-I Antibody, clone SS1A is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.