|Application ||WB, FC|
|Calculated MW||26387 Da|
|Purification||Purified IgG prepared by affinity chromatography|
|Immunogen||Recombinant human TREM-1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Triggering receptor expressed on myeloid cells 1, TREM-1, Triggering receptor expressed on monocytes 1, CD354, TREM1|
|Target/Specificity||Mouse anti Human Trem-1 antibody, clone TREM-37 recognizes Triggering receptor expressed on myeloid cells 1 also known as TREM-1, Triggering receptor expressed on monocytes 1 or CD354. Trem-1 is a 214 amino acid ~22 kDa single pass type 1 transmembrane immune receptor expressed on CD14+ monocytes, macrophages and neutrophils, highly expressed in inflammatory lesions caused by fungi and bacteria. It stimulates neutrophil and monocyte-mediated inflammatory responses. TREM-1 activation, together with LPS and other PRR ligands, amplifies the production pro-inflammatory cytokines and thus the inflammatory response. TREM-1 also plays a crucial role in the mediation of septic shock (Bouchonet al.2001).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human Trem-1 Antibody, clone TREM-37 is for research use only and not for use in diagnostic or therapeutic procedures.|
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