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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti Human CD266 Antibody, clone ITEM-4    

Anti Human CD266 Antibody, clone ITEM-4

Mouse Anti-Human Monoclonal Antibody

     
  • FC - Anti Human CD266 Antibody, clone ITEM-4  ABD12600
    Human CD266 transfected cells stained with Mouse anti Human CD266: Alexa Fluor®647
  • FC - Anti Human CD266 Antibody, clone ITEM-4  ABD12600
    Human CD266 transfected cells stained with Mouse anti Human CD266:RPE
  • FC - Anti Human CD266 Antibody, clone ITEM-4  ABD12600
    Human CD266 transfected cells stained with Mouse anti Human CD266: Alexa Fluor®488
  • FC - Anti Human CD266 Antibody, clone ITEM-4  ABD12600
    Human CD266 transfected cells stained with Mouse anti Human CD266 followed by Rabbit F(ab')2 anti Mouse IgG:RPE
  • FC - Anti Human CD266 Antibody, clone ITEM-4  ABD12600
    Human CD266 transfected cells stained with Mouse anti Human CD266:FITC
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-F, FC
Primary Accession Q9NP84
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names ITEM-4
Calculated MW 13911 Da
Additional Information
Other Species M,Rat
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Human CD266 transfected P815 cells.
Shelf Life 18 months from date of despatch.
Gene ID 51330
Other Names Tumor necrosis factor receptor superfamily member 12A, Fibroblast growth factor-inducible immediate-early response protein 14, FGF-inducible 14, Tweak-receptor, TweakR, CD266, TNFRSF12A, FN14
Target/Specificity Mouse anti Human CD266 antibody, clone ITEM-4 recognizes human Tumor necrosis factor receptor superfamily member 12A, also known as CD266, Fibroblast growth factor-inducible immediate-early response protein 14 or Tweak-receptor. CD266 is a 102 amino acid ~14 kDa type I transmembrane glycoprotein and member of the tumour necrosis factor receptor superfamily (TNFRSF12A) expressed by a variety of tissues, including the heart, lung and kidney, and at elevated levels by human brain and liver tumours.The interaction between CD266 and its ligand CD255 (TWEAK), induces the proliferation and migration of endothelial cells and also angiogenesis, and studies have shown that CD255-induced apoptosis of some tumour cell lines is mediated by CD266 (Nakayamaet al.2003).Mouse anti Human CD266 antibody, clone ITEM-4 is cross-reactive with mouse CD266, and also with Rat-1 fibroblastoid cells in flow cytometry.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human CD266 Antibody, clone ITEM-4 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12600
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