|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Rat thymocyte membrane glycoproteins.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti Rat MHC Class II RT1B antibody, clone OX-6 recognizes a monomorphic determinant of the rat RT1B MHC class II antigen present on B lymphocytes, dendritic cells, some macrophages and certain epithelial cells.Rat MHC Class II RT1B antibody, clone OX-6 does not react with the rat BDIX strain due to a defect in RT1B expression (Maleet al.1987).The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In rats, this complex is referred to as the RT1 region. In mice, this complex is referred to as the H-2 region.Mouse anti Rat MHC Class II RT1B antibody, clone OX-6 also cross reacts with a polymorphic determinant on mouse strains of the H-2 haplotypes k and s. Analysis of recombinant mouse strains has mapped the OX-6 determinant to the H-2I-A region (McMaster and Williams 1979andMaleet al.1987).This product is routinely tested in flow cytometry on rat splenocytes.|
|Preservative & Stabilisers||0.09% Sodium Azide, 1% Bovine Serum|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Rat MHC Class II RT1B Antibody, clone OX-6 is for research use only and not for use in diagnostic or therapeutic procedures.|
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