|Application ||IHC-F, FC, IP|
|Calculated MW||29137 Da|
|Purification||Purified IgG prepared by affinity chromatography|
|Immunogen||Armenian hamster fibroblast line ARHO12 transfected with mouse CD27 cDNA.|
|Shelf Life||18 months from date of despatch.|
|Other Names||CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7|
|Target/Specificity||Hamster anti Mouse CD27 antibody, clone LG.3A10 recogniszes mouse, rat and human CD27, a member of the tumour necrosis factor receptor superfamily. It is expressed in the thymus and spleen, but not in non-lymphoid tissues. CD27 acts as a ligand for CD70, which is expressed in T and B cells, and acts as a costimulatory signal in lymphocyte proliferation and immunoglobulin production.CD27 lacks a death domain in its short cytoplasmic tail, but can induce apoptosis by binding with the apoptosis regulatory protein Siva (also known as CD27-binding protein).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse CD27 Antibody, clone LG.3A10 is for research use only and not for use in diagnostic or therapeutic procedures.|
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