|Application ||IHC-F, IF, FC, IP|
|Calculated MW||128906 Da|
|Purification||Purified IgG prepared by affinity chromatography|
|Immunogen||Mouse intestinal intraepithelial lymphocytes.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Integrin alpha-E, Integrin alpha M290, CD103, Integrin alpha-E light chain, Integrin alpha-E heavy chain, Itgae|
|Target/Specificity||Hamster anti Mouse CD103 antibody, clone 2E7 recognizes mouse CD103, otherwise known as Integrin alpha-E. CD103 binds Integrin beta 7 to form the heterodimeric integrin molecule αEβ7. This complex is sometimes referred to as CD103, though strictly speaking CD103 only refers to the alpha chain. The beta 7 subunit can also interact with other integrin alpha chains. The αEβ7 complex is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. CD103 is expressed on intestinal intraepithelial lymphocytes and is highly expressed on regulatory T cells.Hamster anti Mouse CD103 antibody, clone 2E7 is expected to also recognize the intact αEβ7 complex.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse CD103 Antibody, clone 2E7 is for research use only and not for use in diagnostic or therapeutic procedures.|
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