|Calculated MW||27441 Da|
|Purification||Purified IgG prepared by affinity chromatography|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tumor necrosis factor ligand superfamily member 12, TNF-related weak inducer of apoptosis, TWEAK, Tumor necrosis factor ligand superfamily member 12, membrane form, Tumor necrosis factor ligand superfamily member 12, secreted form, Tnfsf12|
|Target/Specificity||Rat anti Mouse TWEAK antibody, clone MTW-1 recognises mouse TWEAK (TNF-like weak inducer of apoptosis) a type II transmembrane TNF superfamily member. TWEAK binds to the TWEAK receptor FN14 (TWEAK-R) to weakly induce apoptosis in some cell types. It is involved in the induction of inflammatory cytokines. This cytokine also promotes proliferation and migration of endothelial cells and acts as a regulator of angiogenesis. TWEAK is expressed on a broad range of adult and foetal tissues. Rat anti Mouse TWEAK antibody, clone MTW-1 has been reported to block ligand binding in vitro(Nakayamaet al.2003).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse TWEAK Antibody, clone MTW-1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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