|Application ||WB, IHC-P, IHC-F|
|Other Accession||P14136, Q28115, P47819|
|Calculated MW||49900 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Bovine spinal cord homogenate.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Glial fibrillary acidic protein, GFAP, Gfap|
|Target/Specificity||Mouse anti Bovine GFAP antibody, clone 1B4 recognizes glial fibrillary acidic protein, or GFAP, a class III intermediate filament. During development of the central nervous system, GFAP distinguishes astrocytes from other glial cells. It is involved in various cellular functions, such as cell structure and movement, cell communication and the functioning of the blood-brain barrier. It also plays a role in mitosis by adjusting the filament network present in the cell. Defects in GFAP are a cause of Alexander disease, a rare disorder of the central nervous system affecting mostly males. It is a progressive leukoencephalopathy resulting in mental and physical retardation, dementia, seizures and early death. Mouse anti Bovine GFAP antibody, clone 1B4 may be used in conjunction with clones 4A11and2E1 for increased sensitivity when used in immunohistology.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Bovine GFAP Antibody, clone 1B4 is for research use only and not for use in diagnostic or therapeutic procedures.|
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