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>   home   >   Products   >   Primary Antibodies   >   Microbiology   >   Anti Clostridium difficile Toxin B Antibody, clone 5158    

Anti Clostridium difficile Toxin B Antibody, clone 5158

Mouse Anti-Bacterial Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E
Primary Accession P18177
Reactivity Bacteria
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 5158
Calculated MW 269712 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Shelf Life 18 months from date of despatch.
Other Names Toxin B, toxB, tcdB
Target/Specificity Mouse anti Clostridium difficile Toxin B antibody, clone 5158 recognizes Clostridium difficile toxin B. No reaction is observed with toxin A. Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin B (TcdB) is a large exotoxin. Its role in disease is less well understood than that of toxin A, though it seems clear that TcdB contributes to disease. Both toxins modifies the Ras superfamily of small GTPases via glycosylation, inactivating them and leading to the disruption of vital signaling pathways in the cell.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Clostridium difficile Toxin B Antibody, clone 5158 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12631
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(40 western blots)
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