|Application ||WB, IHC-F, IF, E, IP|
|Other Accession||P16858, P04797, P00355, P46406|
|Calculated MW||36053 Da|
|Other Species||H,Pig,Dog,Cat,Rat,M,African Green Monkey ,F,X,Tube-nosed Bat,C,Vertebrates,Sh|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Rabbit muscle GAPDH.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, 220.127.116.11, Peptidyl-cysteine S-nitrosylase GAPDH, 2.6.99.-, GAPDH, GAPD|
|Target/Specificity||Mouse anti Rabbit GAPDH antibody, clone 6C5 recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyse the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin (Haraet al.2006).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Rabbit GAPDH Antibody, clone 6C5 is for research use only and not for use in diagnostic or therapeutic procedures.|
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