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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti Rhodopsin Antibody, clone 1D4    

Anti Rhodopsin Antibody, clone 1D4

Mouse Anti-Bovine Monoclonal Antibody

  • FC - Anti Rhodopsin Antibody, clone 1D4  ABD12635
    Immunochemical staining of adult mouse retinal section with anti-rhodopsin antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02699
Reactivity Bovine
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 1D4
Calculated MW 39008 Da
Additional Information
Other Species Mammalian species,Amphibia
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Bovine rhodopsin.
Shelf Life 18 months from date of despatch.
Gene ID 509933
Other Names Rhodopsin, RHO
Target/Specificity Mouse anti Rhodopsin antibody, clone 1D4 recognises the sequence TETSQVAPA corresponding to aa 340 to 348 of bovine rhodopsin, a pigment of the retina responsible for the formation of photoreceptor cells and the first events in the perception of light. Rhodopsin consists of the protein opsin and a reversibly bound cofactor, retinal, a photoreactive chromophore. Upon light absorption the 11-cis-retinal is isomerised to all-trans retinal, leading to a change in the shape of rhodopsin. The change activates the associated G protein and triggers a second messenger cascade, eventually resulting in the transmission of a nerve impulse to the brain. The trans-retinal is released and converted back into 11-cis-retinal for re-entry into the cycle.Defects in the gene cause various retinopathies such as retinitis pigmentosa and X-linked congenital stationary night blindness.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Rhodopsin Antibody, clone 1D4 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12635
(40 western blots)
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