|Application ||WB, IF|
|Other Accession||P16053, P08553, P07197|
|Calculated MW||95791 Da|
|Immunogen||Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E.coli.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Neurofilament medium polypeptide, NF-M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein, Nefm, Nef3, Nfm|
|Target/Specificity||Mouse anti Rat Neurofilament M antibody, clone 3H11 recognizes the carboxy terminus of rat neurofilament M (NF-M), one of three neurofilament proteins (NF-H, NF-M and NF-L). Neurofilaments are 10nm intermediate filaments found in neurons, with especially high concentrations along the axons, where they appear to control axonal diameter. It is thought that phosphorylation of NF-M results in the formation of interfilament cross-bridges that are important in the maintenance of axonal calibre.Mouse anti Rat Neurofilament M antibody, clone 3H11 also binds to a C- terminal epitope of bovine NF-M.|
|Preservative & Stabilisers||0.065% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Rat Neurofilament M (C-Terminal) Antibody, clone 3H11 is for research use only and not for use in diagnostic or therapeutic procedures.|
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