|Application ||WB, IHC-P, IHC-F|
|Calculated MW||50419 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Synthetic peptide corresponding to Tubulin Beta 3.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tubulin beta-3 chain, Neuron-specific class III beta-tubulin, Tubb3|
|Target/Specificity||Mouse anti Rat Tubulin beta 3 antibody, clone AA10 recognises tubulin beta 3. Dimers of alpha and beta tubulin bind to two GTP molecules and assemble into microtubules. The GTP bound to the beta tubulin subunit eventually hydrolyses into GDP. This GTP cycle is essential for microtubule stability, as dimers bound to GTP tend to assemble into microtubules, whereas dimers bound to GDP tend to be unstable. The tubulin beta 3 chain (also known as neuron-specific class III beta-tubulin) are found exclusively in neurons and serves as a neuronal marker. It has also been found in tumors of neuronal origin.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Rat Tubulin Beta 3 Antibody, clone AA10 is for research use only and not for use in diagnostic or therapeutic procedures.|
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