Anti Tropomodulin 1 (N-Terminal) Antibody, clone TRM-17 (Mab17)
Mouse Anti-Chicken Monoclonal Antibody
|Application ||WB, IF, E, Func|
|Clone Names||TRM-17 (Mab17)|
|Other Species||Birds,Mammalian species|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Recombinant chicken tropomodulin 1|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti Tropomodulin 1 (N-Terminal) antibody, clone TRM-17 recognizes chicken tropomodulin 1, otherwise known as erythrocyte tropomodulin or E-Tmod, an evolutionary very highly conserved cytoskeletal protein .Tropomodulin 1 is a sarcomeric protein highly expressed by erythrocytes, heart and skeletal muscle, which binds to and caps pointed ends of actin filaments to prevent thin filament elongation. The binding of the N-terminal region of Tmod1 with the actin-binding protein tropomyosin blocks the elongation and depolymerization of actin filaments, contributing to the geometry of the membrane skeleton.Mouse anti Tropomodulin 1 (N-Terminal) antibody, clone TRM-17 recognizes an epitope between amino acid residues 6-57 within the N-terminal (NT) region of tropomodulin 1 and inhibits the binding of Tmod1 to tropomyosin.|
|Preservative & Stabilisers||0.05% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Tropomodulin 1 (N-Terminal) Antibody, clone TRM-17 (Mab17) is for research use only and not for use in diagnostic or therapeutic procedures.|
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