|Application ||WB, E, IP|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti Nitrotyrosine antibody, clone 6B2-3G2 recognizes both free and protein-bound nitrotyrosine (Tyr-NO2), including human serum nitro albumin, nitro insulin and nitro haemoglobin.Nitrotyrosine arises from the nitration of protein tyrosine residues, by reactive nitrogen species such as peroxynitrite and nitrogen dioxide, and can be used as a measure of NO-dependent oxidative stress and cell damage. Increased levels of nitrotyrosine are detectable in various pathological conditions including atherosclerosis, rheumatoid arthritis, cardiovascular disease, inflammatory bowel disease and cystic fibrosis (Halliwell 1997).The specificity of Mouse anti Nitrotyrosine antibody, clone 6B2-3G2 as determined by competition ELISA is:Nitrotyrosine:95 % of inhibitionTyrosine:0 % of inhibitionNitrotryptophan:4 % of inhibitionAminotyrosine:0 % of inhibitionPhosphotyrosine:2 % of inhibitionChlorotyrosine:3 % of inhibition|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Nitrotyrosine Antibody, clone 6B2-3G2 is for research use only and not for use in diagnostic or therapeutic procedures.|
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