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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti Mouse Trem-2 Antibody, clone 78.18    

Anti Mouse Trem-2 Antibody, clone 78.18

Rat Anti-Mouse Monoclonal Antibody

  • FC - Anti Mouse Trem-2 Antibody, clone 78.18  ABD12655
    J774 cells stained with Rat anti Mouse TREM2:FITC
  • FC - Anti Mouse Trem-2 Antibody, clone 78.18  ABD12655
    Mouse TREM2 transfected cells stained with Rat anti Mouse TREM2 followed by Goat F(ab')2 anti Rat IgG:RPE (Mouse Adsorbed, STAR73)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99NH8
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG1
Clone Names 78.18
Calculated MW 24527 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Mouse TREM-2 Fc fusion protein.
Shelf Life 18 months from date of despatch.
Gene ID 83433
Other Names Triggering receptor expressed on myeloid cells 2, TREM-2, Triggering receptor expressed on monocytes 2, Trem2, Trem2a, Trem2b, Trem2c
Target/Specificity Rat anti Mouse Trem-2 antibody, clone 78.18 recognizes Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 with Rat anti Mouse Trem-2 antibody, clone 78.18 enhances multinucleated osteoclast formation in vitro. Clone 78.18 may also be used to block TREM-2 on pre-osteoclasts to inhibit the formation of multinuclear osteoclasts and to inhibit bone resorption by mature osteoclasts.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Mouse Trem-2 Antibody, clone 78.18 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12655
(40 western blots)
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