|Application ||WB, IHC-F, FC, IP|
|Calculated MW||18172 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Rat Thy1 antigen.|
|Shelf Life||18 months from the date of despatch|
|Other Names||Thy-1 membrane glycoprotein, Thy-1 antigen, CD90, Thy1, Thy-1|
|Target/Specificity||Mouse anti Rat CD90 antibody, clone OX-7 recognizes rat and CD90, also known as Thy1.1, a GPI-anchored membrane protein containing a single V type Ig-like domain CD90 is expressed on a variety of cell types including thymocytes, neuronal cells, stem cells, immature B cells and connective tissues, CD90 is also expressed in T cells in mice.Since Thy1.1 is a monomorphic determinant in rat but polymorphic in mice, clone MRC OX-7 reacts with Thy1.1 mice e.g. AKR and FVB mice, but not Thy1.2 mice such as CBA and BALB/c. The affinity of the Fab' of MRC OX-7 for rat Thy1 is 3 x 109m1 and for mouse Thy1.1 is 3 x 108m-1(1).Mouse anti rat CD90, clone MRC OX-7 has been demonstrated to promote neurite outgrowths on peripherin-stained sympathetic rat neurons, using fluorescence microscopy (Jenget al.1998). Clone OX-7 has also been reported to induce glomerular nephritis in Wistar rats (Tamuraet al.1996).This product is routinely tested in flow cytometry on rat thymocytes.|
|Preservative & Stabilisers||None present|
|Storage||Store at -20℃ only.|
|Precautions||Anti Rat CD90 Antibody, clone OX-7 is for research use only and not for use in diagnostic or therapeutic procedures.|
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