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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti Human CD300a Antibody, clone P192    

Anti Human CD300a Antibody, clone P192

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti Human CD300a Antibody, clone P192  ABD12762
    Human peripheral blood monocytes stained with Mouse anti Human CD300a followed by Rabbit F(ab')2 anti Mouse IgG:FITC
  • FC - Anti Human CD300a Antibody, clone P192  ABD12762
    Human peripheral blood monocytes stained with Mouse anti Human CD300a:RPE
  • FC - Anti Human CD300a Antibody, clone P192  ABD12762
    Human peripheral blood monocytes stained with Mouse anti Human CD300a:FITC
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UGN4
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names P192
Calculated MW 33201 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Polyclonal population of NK cells
Shelf Life 18 months from the date of despatch
Gene ID 11314
Other Names CMRF35-like molecule 8, CLM-8, CD300 antigen-like family member A, CMRF-35-H9, CMRF35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin superfamily member 12, IgSF12, Inhibitory receptor protein 60, IRp60, NK inhibitory receptor, CD300a, CD300A, CMRF35H, IGSF12
Target/Specificity Mouse anti Human CD300a antibody, clone P192 specifically recognizes human CD300a, otherwise known as IRp60 (inhibitory receptor protein 60), a 60kDa transmembrane glycoprotein expressed by natural killer cells (NK), T and B cell subsets, monocytes, neutrophils, macrophages, granulocytes, dendritic cells (DC) and mast cells.Studies have shown that the cross-linking of CD300a on NK results in a down-regulation of their cytolytic activity, whilst cross-linking of CD300a on mast cells, inhibits IgE-induced degranulation and SCF-mediated survival. Furthermore, cross-linking of CD300a on the surface of eosinophils has been shown to significantly inhibit their survival, chemotaxis and activation in response to certain inflammatory cytokines, whilst eosinophil-derived MBP (major basic protein) and EDN (neurotoxin), can down-regulate CD300a expression on mast cells in vitro.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human CD300a Antibody, clone P192 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12762
(40 western blots)
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