Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Anti Mouse TIM-2 Antibody, clone RMT2-25    

Anti Mouse TIM-2 Antibody, clone RMT2-25

Rat Anti-Mouse Monoclonal Antibody

  • FC - Anti Mouse TIM-2 Antibody, clone RMT2-25  ABD12792
    TIM-2 transfected NRK cells stained with Rat anti Mouse TIM-2:FITC
  • FC - Anti Mouse TIM-2 Antibody, clone RMT2-25  ABD12792
    TIM-2 transfected NRK cells stained with Rat anti Mouse TIM-2
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, FC, IP, Func
Primary Accession Q8R183
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names RMT2-25
Calculated MW 33504 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Tim-2-Ig, consisting of amino acids 1-230 of mouse Tim-2, coupled with the Fc portion of mouse IgG2a.
Shelf Life 18 months from date of despatch.
Gene ID 171284
Other Names T-cell immunoglobulin and mucin domain-containing protein 2, TIMD-2, T-cell immunoglobulin mucin receptor 2, TIM-2, T-cell membrane protein 2, Timd2, Tim2
Target/Specificity Rat anti Mouse TIM-2 antibody, clone RMT2-25 recognizes mouse Tim-2 (T-cell immunoglobulin mucin 2), a transmembrane glycoprotein and member of the immunoglobulin superfamily, expressed by activated lymphocytes, developmentally in the 8-cell embryo and blastocyst, and preferentially up-regulated in Th2 cells and down-regulated in Th1 cells.Tim-2 acts as a negative regulator of Th2 cells, and is implicated to play a critical role in the development of atopic disease and other Th2-biased immune responses. Tim-2 also acts as a receptor for Semaphorin 4A, a transmembrane protein expressed on dendritic cells and B cells, which plays a role in the guidance of axonal migration during neuronal development, and has been shown to enhance T cell activation.Studies using Rat anti Mouse TIM-2 antibody, clone RMT2-25 in mouse, have shown that signaling by Tim-2 can influence the proliferation and antibody production of B cells, during early phase collagen-induced arthritis (Kawamoto et al. 2011).Rat anti Mouse TIM-2 antibody, clone RMT2-25 has been shown to significantly enhance the proliferation of stimulated splenic B cells in vitro(Kawamoto et al. 2011).
Preservative & Stabilisers None present
Storage Store at -20℃ only.
PrecautionsAnti Mouse TIM-2 Antibody, clone RMT2-25 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

Cat# ABD12792
(40 western blots)
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanKoreaLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Santa Cruz Alternative
Terms & Conditions