|Application ||IF, FC|
|Calculated MW||103671 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Purified murine TLR3 extracellular domain protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Toll-like receptor 3, CD283, Tlr3|
|Target/Specificity||Rat anti Mouse CD283 anribody, clone 11F8 recognizes mouse TLR3, otherwise known as CD283 or Toll-like receptor 3. CD283 is a 905 amino acid ~105 kDa single pass type 1 transmembrane glycoprotein associated with endosomal membranes and member of the Toll-like receptor (TLR) family. CD283 functions as a receptor for double-stranded RNA (UniProt: Q99MB1).TLRs are expressed on the cell surface and the endocytic compartment and recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents.They also initiate cell signalling to induce production of cytokines necessary for the innate immunity and subsequent adaptive immunity.|
|Preservative & Stabilisers||0.09% Sodium Azide, 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse CD283 Antibody, clone 11F8 is for research use only and not for use in diagnostic or therapeutic procedures.|
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