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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti Mouse CD283 Antibody, clone 11F8    

Anti Mouse CD283 Antibody, clone 11F8

Rat Anti-Mouse Monoclonal Antibody

  • FC - Anti Mouse CD283 Antibody, clone 11F8  ABD12801
    Mouse spleen cells stained with Rat anti Mouse CD8 alpha:APC and (A) Rat anti Mouse CD283 or (B) rat IgG control. Detection with Goat anti Rat IgG:Dylight®488 was performed following permeabilisation of the cells with Leucoperm™ prior to incubation with Rat anti Mouse CD283
  • FC - Anti Mouse CD283 Antibody, clone 11F8  ABD12801
    Mouse spleen cells stained with Rat anti Mouse CD8 alpha:APC and (A) Rat anti Mouse CD283:FITC or (B) rat IgG control. Staining was performed following permeabilisation of the cells with Leucoperm™ and incubation with Mouse Seroblock FCR
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99MB1
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names 11F8
Calculated MW 103671 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Purified murine TLR3 extracellular domain protein.
Shelf Life 18 months from date of despatch.
Gene ID 142980
Other Names Toll-like receptor 3, CD283, Tlr3
Target/Specificity Rat anti Mouse CD283 anribody, clone 11F8 recognizes mouse TLR3, otherwise known as CD283 or Toll-like receptor 3. CD283 is a 905 amino acid ~105 kDa single pass type 1 transmembrane glycoprotein associated with endosomal membranes and member of the Toll-like receptor (TLR) family. CD283 functions as a receptor for double-stranded RNA (UniProt: Q99MB1).TLRs are expressed on the cell surface and the endocytic compartment and recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents.They also initiate cell signalling to induce production of cytokines necessary for the innate immunity and subsequent adaptive immunity.
Preservative & Stabilisers 0.09% Sodium Azide, 1% Bovine Serum Albumin
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Mouse CD283 Antibody, clone 11F8 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12801
(40 western blots)
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