|Calculated MW||33020 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Bovine FcγRII-transfected COS7 cells|
|Shelf Life||18 months from date of despatch.|
|Other Names||Low affinity immunoglobulin gamma Fc region receptor II, IgG Fc receptor II, Fc-gamma RII, FcRII, CD32, FCGR2|
|Target/Specificity||Mouse anti Bovine CD32 antibody, clone CCG39, recognizes the bovine homologue of human CD32, one of a group of Fc receptors belonging to the immunoglobulin superfamily and involved in phagocytosis of opsonized microbes. Bovine CD32 is a single pass type 1 membrane protein of approximately 32kDa, expressed on the cell surface of most cells including B-lymphocytes, monocytes, neutrophils and afferent veiled lymph dendritic cells Chatthaet al.2010. It has been shown that expression of bovine CD32 is higher on macrophages than on neutrophils.CD32 can function in an inhibtory capacity to antibody production and is the low affinity Fc receptor for IgG (FcRII), binding to the Fc region of immunoglobulin gamma Chatthaet al.2009.Mouse anti Bovine CD32, clone CCG39 is one of a number of anti bovine CD32 reagents available from AbD Serotec, clone CCG39 is of interest in that it is specific to bovine CD32 and does not recognizes ovine CD32. For detection of ovine CD32, clone CCG36, which cross reacts with ovine CD32, may be used.|
|Preservative & Stabilisers||0.09% Sodium Azide, 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Bovine CD32 Antibody, clone CCG39 is for research use only and not for use in diagnostic or therapeutic procedures.|
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