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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Anti Human Beta Amyloid (aa37-42) Antibody, clone MAb1.1    

Anti Human Beta Amyloid (aa37-42) Antibody, clone MAb1.1

Mouse Anti-Human Monoclonal Antibody

  • IHC-P - Anti Human Beta Amyloid (aa37-42) Antibody, clone MAb1.1  ABD12809
    Staining of paraffin embedded human Alzheimer’s disease brain tissue with Mouse anti Human beta amyloid and detected using a Goat anti Mouse IgG:HRP secondary antibody. Top image: 5x magnification showing diffuse plaques in Alzheimer’s disease brain. Bottom left image: 20x magnification showing diffuse plaques in Alzheimer’s disease brain. Bottom right image: Alzheimer’s disease brain stained with an unrelated antibody as negative control
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05067
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names MAb1.1
Calculated MW 86943 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen A construct of the last six amino acids of Aβ42 (GGVVIA) and a potent T-cell epitope from Chlamydia pneumonia CWL pmp8-protein, synthesised directly onto an LPA scaffold (See Axelsenet al. for full details).
Shelf Life 18 months from date of despatch.
Gene ID 351
Other Names Amyloid beta A4 protein, ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, Beta-amyloid protein 40, Beta-APP40, C83, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59, Amyloid intracellular domain 59, AICD-59, AID(59), Gamma-CTF(59), Gamma-secretase C-terminal fragment 57, Amyloid intracellular domain 57, AICD-57, AID(57), Gamma-CTF(57), Gamma-secretase C-terminal fragment 50, Amyloid intracellular domain 50, AICD-50, AID(50), Gamma-CTF(50), C31, APP, A4, AD1
Target/Specificity Clone Mab1.1 recognises Beta-amyloid protein 42 (also known as Aβ42), the 42 amino acid peptide processed from Amyloid precursor protein (APP). There are several forms of Aβ peptides processed from APP, the most common being Aβ40 and Aβ42. Amyloid plaques contain both Aβ40 and Aβ42. Aβ40 is more common, but Aβ42 more fibrillogenic and therefore associated with disease states such as Alzheimer’s disease.Clone Mab1.1 specifically binds to the 37-42aa region, and does not recognise full-length APP or the 40 amino acid peptide processed from APP (Aβ40). It stains diffuse plaques found in the brain of Alzheimer’s disease patients. It does not stain healthy brain tissue or other organs.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human Beta Amyloid (aa37-42) Antibody, clone MAb1.1 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12809
(40 western blots)
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