|Calculated MW||37266 Da|
|Immunogen||NKP46-IgG1 Fc fusion protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Natural cytotoxicity triggering receptor 1, Activating receptor 1, mAR-1, Lymphocyte antigen 94, Natural killer cell p46-related protein, NK-p46, NKp46, mNKp46, CD335, Ncr1, Ly94|
|Target/Specificity||Rat anti Mouse CD335 antibody, clone 29A1.4 recognizes natural killer cell p46-related protein (NKp46), otherwise known as CD335, which is uniquely expressed by resting and activated natural killer (NK) cells, but no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes. It is a major NK cell lysis receptor for autologous pathogen-infected and tumor target cells during natural cytotoxicity responses. Ligands of CD335 include viral hemagglutinins (HAs) and heparan sulfate proteoglycans (HSPGs) on the surface of tumor cells. Staining with Rat anti mouse CD335 (29A1.4) is not strain specific and the antibody has been used to stain C57BL/6, SJL, CBA/CA and BALB/c strains. Clone 29A1.4 also activates NK cells in vitro. It does not deplete NK cells in vivo.|
|Preservative & Stabilisers||0.09% Sodium Azide, 1% Bovine Serum|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse CD335 Antibody, clone 29A1.4 is for research use only and not for use in diagnostic or therapeutic procedures.|
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