|Calculated MW||40076 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Human Thymocytes followed by peripheral blood mononuclear cells.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form, CD14|
|Target/Specificity||Mouse anti Human CD14 antibody, clone UCHM1 recognizes a cell surface antigen of 55 kDa, known as CD14.The CD14 molecule is found predominantly on monocytes and macrophages in flow cytometry, it is less strongly expressed on granulocytes, and is absent from stem cells and myeloid cells of very early differentiation states. In immunohistology the CD14 molecule is found to be present on Langerhans cells, follicular dendritic cells, histiocytes and high endothelial venules. Antibodies to the CD14 molecule are known to induce oxidative burst formation. In tonsil tissue sections UCHM1 gives positive staining reactions with monocytic cells, the interfollicular tissue macrophages seen under the capsule, and dendritic reticulum cells. Skin Langerhans cells are always negative (Hogget al.1984). UCHM1 also reacts with Kupffer cells and sinus lining cells on the liver.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3),Sucrose|
|Storage||Store at +4℃. DO NOT FREEZE.|
|Precautions||Anti Human CD14 Antibody, clone UCHM1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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