|Application ||IHC-F, FC, Func|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Rat spleen cell homogenate|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||ABD12825 recognises a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. Like ED8, ED7 recognises small ramified microglia in the central nervous system. No other cell types are positive for ED7, except for the cilia of the bronchus epithelium. The recognised antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules (CD11b/CD18). ED7 and ED8 may recognise closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.|
|Preservative & Stabilisers||0.09%Sodium Azide|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Rat CD11b Antibody, clone ED7 is for research use only and not for use in diagnostic or therapeutic procedures.|
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