|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Rat spleen cell homogenate with Freund's complete adjuvant.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti Rat CD11b antibody, clone ED8 recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. It also recognizes small ramified microglia in the central nervous system. No other cell types are positive for ED8. The recognized antigen is a heterodimer (160 and 95 kD) belonging to the family of adhesion molecules CD11b/CD18, also designated as Mac-1 antigen or CR3. Mouse anti Rat CD11b antibody, clones ED7 and ED8 may recognize closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.|
|Preservative & Stabilisers||0.09% Sodium Azide, 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Rat CD11b Antibody, clone ED8 is for research use only and not for use in diagnostic or therapeutic procedures.|
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