|Calculated MW||127481 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||T cell enriched splenocytes from B10 mice|
|Shelf Life||18 months from date of despatch.|
|Other Names||Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CD11b, Itgam|
|Target/Specificity||Rat anti Mouse CD11b antibody, clone M1/70.15 recognizes the murine CD11b cell surface antigen also known as the alpha M integrin chain or MAC-1, a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Rat anti Mouse CD11b antibody, clone M1/70.15 has been reported to block iC3b binding to its receptor (Belleret al.1982).Rat anti Mouse CD11b antibody, clone M1/70.15 has been reported to as being suitable for use on PLP fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue (Whitelandet al.1995). This product is routinely tested in flow cytometry on mouse peritoneal macrophages.|
|Preservative & Stabilisers||0.09% Sodium Azide, 1% Bovine Serum|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse CD11b Antibody, clone M1/70.15 is for research use only and not for use in diagnostic or therapeutic procedures.|
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