|Application ||IHC-F, IF, FC, E, IP|
|Calculated MW||51548 Da|
|Purification||Purified IgG prepared by ion exchange chromatography|
|Immunogen||CHO cells transfected with cDNA of the IL-6 receptor.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Membrane glycoprotein 80, gp80, CD126, IL6R|
|Target/Specificity||Mouse anti Human CD126 antibody, clone B-R6 recognizes human Interleukin-6 receptor subunit alpha, also known as CD126, IL-6R or Membrane glycoprotein 80. Human CD126 is a 468 amino acid single pass type I transmembrane glycoprotein bearing a single Ig-like C2 type domain, two fibronectin type III domains and a single WSXWS motif which may be involved in receptor avtivation (Daqilet al.2012).Mouse anti Human CD126 antibody, clone B-R6 inhibits IL-6 mediated proliferation of XG-1 cells (Luet al.1995) and partially blocks binding of IL-6 to its receptor (Fourcinet al.1994), clone B-R6 recognizes both the soluble and membranous human CD126Removal of Sodium azide is recommended prior to use in functional assays. The use of EQU003 for this purpose.|
|Preservative & Stabilisers||0.09%Sodium Azide|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human CD126 (Il-6R) Antibody, clone B-R6 is for research use only and not for use in diagnostic or therapeutic procedures.|
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