|Application ||WB, IHC-P, IHC-F, IF, FC|
|Calculated MW||30015 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Synthetic peptide GRGTKF corresponding to C terminal region of myelin proteolipid protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Myelin proteolipid protein, PLP, Lipophilin, PLP1, PLP|
|Target/Specificity||Mouse anti myelin proteolipid protein antibody, clone plpc1 recognizes myelin proteolipid protein (PLP) in many mammalian species (Stoffelet al.1985). Clone plpc1 also recognizes the alternative PLP splice variant lacking part of the cytoplasmic domain (amino acids 117-151), known as DM20 (Simonset al.1987) .PLP encodes the major protein components of compact CNS myelin and mutations in the PLP gene can lead to severe dysmyelinating disease (Hudsonet al.1989).Mouse anti myelin proteolipid protein, clone plpc1 has proved a useful immunohistochemical tool for the study of central nervous system injury in patients with multiple sclerosis (Seewanet al.2011,Huizingaet al.2011)|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Myelin Proteolipid Protein Antibody, clone plpc1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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