|Application ||IHC-P, IHC-F, FC|
|Calculated MW||13242 Da|
|Other Species||Hs,Pig,Dog,Rb,Baboon,B,Fallow deer,Pygmy hippopotamus,Mink,Gp,Rat,Cat,Cynomolgus monkey,Rh,Ga|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Shelf Life||18 months from the date of despatch|
|Other Names||Protein S100-A9, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9, S100A9, CAGB, CFAG, MRP14|
|Target/Specificity||Mouse anti Human macrophages, clone MAC387 recognizes the L1 or Calprotectin molecule, an intracytoplasmic antigen comprised of a 12 kDa alpha chain and a 14 kDa beta chain. Although originally described as binding to epitopes common to both the alpha and beta chains (Flavellet al.1987) subsequent studies indicate that the antibody detects an epitope exclusively expressed on the beta chain (Goebeleret al.1994) demonstrated by immunofluorescent and western blotting on both naturally expressing and transfected targets. In addition Mouse anti Human macrophages, clone MAC387 detects the beta chain in complex with the alpha.The antigen recognized by Mouse anti Human macrophages, clone MAC387 is expressed by granulocytes, monocytes and by tissue macrophages. Variable results have been reported for staining brain macrophages and microglia. The epitope recognized appears to be well conserved and the antibody is routinely used for the detection of myeloid cellds in a wide range of species.|
|Preservative & Stabilisers||None present|
|Storage||Store at -20℃ only.|
|Precautions||Anti Human Macrophages Antibody, clone MAC387 is for research use only and not for use in diagnostic or therapeutic procedures.|
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