|Application ||WB, FC, IP, Func|
|Calculated MW||41400 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Human fibroblast cell line.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Complement decay-accelerating factor, CD55, CD55, CR, DAF|
|Target/Specificity||Mouse anti Human CD55 antibody, clone BRIC216 recognizes the CD55 antigen, a ~70 kDa glycoprotein also known as Decay Accelerating Factor (DAF). CD55 is distributed on erythrocytes and other circulating blood cells and also on cells in non-haemopoietic tissue particularly epithelium and endothelium. CD55 is also expressed at the foetal-maternal interfaces in placenta.CD55 has reduced expression on individuals with paroxysmal nocturnal haemoglobinuria. Mouse anti Human CD55 antibody, clone BRIC216 has a functional binding affinity to erythrocytes of 8.7 x 107M-1. The antigen is pronase and trypsin resistant and chymotrypsin sensitive. Mouse anti Human CD55 antibody, clone BRIC216 recognises the consensus region 3 of the DAF molecule, which contains the functional site, and the antibody blocks the function of DAF.|
|Preservative & Stabilisers||0.09%Sodium Azide|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human CD55 Antibody, clone BRIC216 is for research use only and not for use in diagnostic or therapeutic procedures.|
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