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Anti Human CD49d Antibody, clone 44H6

Mouse Anti-Human Monoclonal Antibody

     
  • FC - Anti Human CD49d Antibody, clone 44H6  ABD12915
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD49d:RPE
  • FC - Anti Human CD49d Antibody, clone 44H6  ABD12915
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD49d: Low Endotoxin
  • FC - Anti Human CD49d Antibody, clone 44H6  ABD12915
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD49d: FITC
  • FC - Anti Human CD49d Antibody, clone 44H6  ABD12915
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD49d
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-F, FC
Primary Accession P13612
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 44H6
Calculated MW 114900 Da
Additional Information
Purification Purified IgG prepared by ion exchange chromatography
Immunogen HOON pre-B leukaemia cell line.
Shelf Life 18 months from the date of despatch
Gene ID 3676
Other Names Integrin alpha-4, CD49 antigen-like family member D, Integrin alpha-IV, VLA-4 subunit alpha, CD49d, ITGA4, CD49D
Target/Specificity Mouse anti Human CD49d monoclonal antibody, clone 44H6 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ~150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemleret al.1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer’s patch high endothelial venules and postcapillary venules in lamina propria (Briskinet al.1997)Mouse anti human CD49d, clone 44H6 is reported to induce homotypic aggregation of pre-B cell lines including HOONandNALM-6(Letarteet al.1993).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4oC or at -20oC if preferred.
PrecautionsAnti Human CD49d Antibody, clone 44H6 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12915
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