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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Anti Human Alpha 1 Antichymotrypsin Antibody    

Anti Human Alpha 1 Antichymotrypsin Antibody

Sheep Anti-Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01011
Reactivity Human
Host Sheep
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 47651 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography
Immunogen Native, purified
Shelf Life 18 months from date of despatch.
Gene ID 12
Other Names Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less, SERPINA3, AACT
Target/Specificity Sheep anti Human alpha 1 antichymotrypsin antibody detects human alpha 1 antichymotrypsin (AACT), a member of the serpin superfamily of serine proteinase inhibitors. AACT has a molecular weight of ~68kDa, and functions to protect the lower respiratory tract from proteolytic damage by inhibiting chymotrypsin-like proteinases, and also plays a role in the acute phase response.Polymorphisms in AACT appear to be tissue specific and influence protease targeting, and mutations in its gene have been implicated in the pathogenesis of Alzheimer's disease (AD). AACT levels are elevated in the cerebrospinal fluid of AD patients and elevated levels are also associated with AD severity.
Preservative & Stabilisers 0.09% Sodium Azide, 1% Bovine Serum Albumin
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human Alpha 1 Antichymotrypsin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13135
(40 western blots)
Availability: Inquire
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