|Application ||WB, IHC-P, FC, E, Func|
|Calculated MW||42856 Da|
|Immunogen||Synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acids 2-22 of mouse CD197.|
|Shelf Life||18 months from date of despatch.|
|Other Names||C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, Epstein-Barr virus-induced G-protein coupled receptor 1, EBI1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, CD197, Ccr7, Cmkbr7, Ebi1, Ebi1h|
|Target/Specificity||Goat anti Mouse CD197 antibody recognizes mouse C-C chemokine receptor type 7, also known as CD197, CCR7, Epstein-Barr virus-induced G-protein coupled receptor 1 or MIP-3 beta receptor. CD197 is a 378 amino acid ~43 kDa multi pass type III transmembrane glycoprotein and member of the G-protein coupled receptor 1 family (UniProt: P74447). CD197 is expressed by various lymphoid tissues, activated B and T cells, naive T cells, NK cells and dendritic cells (DCs), which acts a high-affinity receptor for the chemokines MIP-3beta (CCL19) and CCL21.Ligand binding of CD197 plays a vital role in the homing of naive T cells and antigen-loaded DCs into secondary organs. Expression of CD197 is strongly up-regulated in B cells infected with Epstein-Barr virus (EBV) and T cells infected with herpesvirus 6 or 7. Goat anti Mouse CD197 antibody can be used in research studies to distinguish between central memory and effector memory T cells and is reported as suitable for use in immunocytochemistry.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at -20℃ only.|
|Precautions||Anti Mouse CD197 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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