|Application ||WB, IHC-P, E, Func|
|Calculated MW||10212 Da|
|Immunogen||Recombinant human MIP-1 beta.|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||C-C motif chemokine 4, G-26 T-lymphocyte-secreted protein, HC21, Lymphocyte activation gene 1 protein, LAG-1, MIP-1-beta(1-69), Macrophage inflammatory protein 1-beta, MIP-1-beta, PAT 744, Protein H400, SIS-gamma, Small-inducible cytokine A4, T-cell activation protein 2, ACT-2, MIP-1-beta(3-69), CCL4, LAG1, MIP1B, SCYA4|
|Target/Specificity||Rabbit anti Human MIP-1 beta antibody recognizes human MIP-1 beta, otherwise known as CCL4, a 69 amino acid member of the CC chemokine family, shown to signal through the chemokine receptors CCR1, CCR2 and CCR5.MIP-1 beta is involved in host defence against invading pathogens, acting as a regulator of activation and trafficking of inflammatory cells, such as monocytes, B cells, NK cells, neutrophils, dendritic cells and CD4+ lymphocytes.The secretion of MIP-1 beta by CD8+ lymphocytes has been shown to act as a major HIV-suppressive factor (HIV-SF) through binding to CCR5, identified as a coreceptor for HIV-1 target cell entry.|
|Preservative & Stabilisers||None present|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human MIP-1 Beta Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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