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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti Human CD156b (C-Terminal) Antibody    

Anti Human CD156b (C-Terminal) Antibody

Goat Anti-Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P78536
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 93021 Da
Additional Information
Immunogen Peptide with sequence LQRQNRVDSKETEC from the C-terminus of CD156b.
Shelf Life 18 months from date of despatch.
Gene ID 6868
Other Names Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17,, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b, ADAM17, CSVP, TACE
Target/Specificity Goat anti Human CD156b antibody detects an epitope within the C-terminus of isoform 1 of CD156b, a ~125 kDa type I transmembrane glycoprotein which belongs to the ADAM (a disintegrin and metalloprotease domain) family. CD156b functions as a tumour necrosis factor-alpha converting enzyme (TACE). CD156b also causes a number of inflammatory modulators to undergo ectodomain shedding, including TNFR75, IL-1RII, TNFR55, L-selectin, and the amyloid precursor protein among others. CD156b plays a prominent role in the activation of the Notch signalling pathway.ADAM17 plays a pivotal role in several acquired tumor cell capabilities by mediating the availability of soluble transforming growth factor-alpha, and establishing an autocrine signaling pathway through endogenous EGFR activation. CD156b is therefore a prospective therapeutic target in human cancer.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human CD156b (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13260
(40 western blots)
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
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