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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti Human Focal Adhesion Kinase Antibody    

Anti Human Focal Adhesion Kinase Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC-P - Anti Human Focal Adhesion Kinase Antibody  ABD13267
    Staining of formalin fixed, paraffin embedded human ductal and lobular epithelium with Rabbit anti Human focal adhesion kinase
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q05397
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 119233 Da
Additional Information
Immunogen Synthetic 16 amino acid peptide for the internal domain of human focal adhesion kinase.
Shelf Life 18 months from date of despatch.
Gene ID 5747
Other Names Focal adhesion kinase 1, FADK 1,, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK, PTK2, FAK, FAK1
Target/Specificity Rabbit anti Human Focal Adhesion Kinase antibody recognizes human focal adhesion kinase 1, also known as Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71 or Protein-tyrosine kinase 2. Focal adhesion kniase belongs to the Tyr protein kinase family and contains a single FERM domain and a single protein kinase domain. Rabbit anti Human Focal Adhesion Kinase antibody detects an epitope within the internal region of Focal adhesion kinase (FAK), a 125kD cytoplasmic protein tyrosine kinase that is activated by numerous stimuli and controls cell motility, proliferation and apoptosis. FAK resides at focal adhesions that form between cells growing in the presence of extracellular matrix constituents (Brami-Cherrieret al.2014).FAK is a highly conserved molecule amongst vertebrate species and the immunogen sequence domonstrates 100% identity with mouse, rat, many non-human primates, bovine, rabbit and chicken species.FAK plays a potential role in oncogenic transformation, and its expression is thought to be correlated to tumour invasiveness (Ibbetsonet al.2013).
Preservative & Stabilisers 0.1% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human Focal Adhesion Kinase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13267
(40 western blots)
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